Rosa IACOVINO
Insegnamento di BIOMOLECULAR STRUCTURE DETERMINATION BY NMR AND X-RAY
Corso di laurea magistrale in MOLECULAR BIOTECHNOLOGY
SSD: CHIM/03
CFU: 8,00
ORE PER UNITÀ DIDATTICA: 64,00
Periodo di Erogazione: Secondo Semestre
Italiano
Lingua di insegnamento | INGLESE |
Contenuti | |
Testi di riferimento | |
Obiettivi formativi | |
Prerequisiti | |
Metodologie didattiche | |
Metodi di valutazione | |
Altre informazioni | |
Programma del corso |
English
Teaching language | English |
Contents | In the first part of this course (NMR) the principles of how obtain and evaluate complex spectra |
Textbook and course materials | Understanding NMR Spectroscopy, 2nd Edition. |
Course objectives | The aim of this course is to introduce the theory and practice for the structural characterization |
Prerequisites | No propedeutics |
Teaching methods | The attendance to the lessons is mandatory. The course is organized in 52 hours of frontal lessons that will be theoretical and practical. Further 12 hours will be dedicated to the lab practice ( six 2 hours practices). During such experiences, that will be performed in groups of two or three components, the students will learn how to characterize the structural the molecular and supramolecular structure of Biomolecules by using NMR and X-ray data. Moreover, During the course |
Evaluation methods | The final examination will consist in an oral interview, aimed to verify the notion acquired and the ability of the student to re-elaborates the contents presented during the course. In particular, the oral examinations are aimed to evaluate the capability of reasoning and connecting the various arguments of the course and, i.e. the basic concepts of NMR, the application of NMR to drug discovery and the basic concepts of X-ray crystallography, is constituted by questions about the theoretical part of the course to evaluate the knowledge of the studied subjects and the capability to organize the exposition and connection of the diverse arguments. |
Other information | During the course slides and notes of the lectures will be provided to the students via the Web site of the University of Campania “L. Vanvitelli” (sharepoint) |
Course Syllabus | Fundamentals of modern NMR spectroscopy: Spin magnetization; Vector model; Rotating |